RECENT UPDATE ON ANTI-CANCER ACTIVITY OF GYNURA PROCUMBENS (LOUR.) MERR.

Received 2023-01-08; Accepted 2023-03-21; Published 2023-06-06

Authors

  • Rafeezul Mohamed Department of Biomedical Science, Advanced Medical and Dental Institute, Universiti Sains Malaysia, Bertam, 13200 Kepala Batas, Pulau Pinang, Malaysia.
  • Lim Vuanghao Department of Biomedical Science, Advanced Medical and Dental Institute, Universiti Sains Malaysia, Bertam, 13200 Kepala Batas, Pulau Pinang, Malaysia.
  • Mohd Yusmaidie Aziz Department of Toxicology, Advanced Medical and Dental Institute, Universiti Sains Malaysia, Bertam, 13200 Kepala Batas, Pulau Pinang, Malaysia.

DOI:

https://doi.org/10.22452/jummec.sp2023no1.6

Abstract

Gynura procumbens (Lour.) Merr. is a traditional medicinal herb that is utilised to treat a wide range of illnesses, such as kidney disease, hypertension, eruptive fever, snake bites, migraines, diabetes, and rheumatism. Gynura procumbens was also found to exhibit anti-cancer effects, especially related to cervical, breast, leukemia, and osteosarcoma cancers. Nevertheless, the exact mechanisms of its anti-cancer effects are still under investigation. The aim of this study is to provide updated information on ongoing studies which focused on the benefits of Gynura procumbens herb in preventing various types of cancers. Google and PubMed were explored using the keywords “Gynura procumbens and cancer” by selecting published journals on the anti-cancer effects of Gynura procumbens. This review has highlighted the botanical aspects, chemical constituents, and anti-cancer effects of Gynura procumbens on selected types of cancers as have been reported by previous studies. The study findings have implications on future research which pave way for future clinical usage, either alone or in combination with the currently available medicines in treating cancers.

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Published

2023-06-06