TRANSIENT GLOBAL AMNESIA POST COVID-19 VACCINE: A CASE REPORT

Received 2023-08-20; Accepted 2023-10-31; Published 2024-02-21

Abstract

The roles of the nervous system in the aftermath of COVID-19 vaccination is currently being studied more thoroughly. Here, we present a case of transient global amnesia (TGA) that occurred in a 44-year-old male shortly after receiving the Pfizer COVID-19 vaccine. The patient experienced sudden and profound anterograde amnesia with no associated focal neurological deficits. His symptoms included seizures that lasted for less than 24-hours post-vaccination. His test results, including chest X-ray, EEG, and a brain MRI, were negative. We aim to investigate the potential link between the vaccination and development of TGA by providing a case description with documented clinical presentations and diagnostic workup in order to establish any temporal association between the COVID-19 vaccination and the onset of TGA, including the vaccine type, and the time elapsed between vaccination and the symptoms onset. This case contributes to the emerging understanding of potential neurological events following COVID-19 vaccination. It underscores the importance of close monitoring for unusual post-vaccination symptoms and encourages further investigations into the mechanisms underlying TGA post-vaccination. Timely diagnosis and supportive care were crucial in the patient's recovery.